Research

Authors: M. Arata, Z. Sternberg Institution: Synergy Health Concepts, Newport Beach, CA Background Chronic cerebrospinal venous insufficiency (CCSVI) has been described as a condition resulting from impaired CNS venous drainage. Venous balloon angioplasty (BA) has been performed as a treatment for CCSVI. Autonomic nervous system (ANS) dysfunction has been proposed as mechanism underlying the occurrence […]

Authors: Michael A. Arata, M.D. Institution: Synergy Health Concepts, Newport Beach, CA Background Patients undergoing central venous angioplasty (CVA) have demonstrated improvement in autonomic parameters. We hypothesize that this results from stimulation of low pressure baroreceptors during balloon inflation. This report describes the assessment of the autonomic effect of CVA using HRV parameters. Further, the […]

Authors: Michael A. Arata, M.D., Zohara Sternberg, Ph.D., Steven Cen, Ph.D. Institution: Synergy Health Concepts, Newport Beach, CA Purpose Chronic cerebrospinal venous insufficiency (CCSVI) has been described as a condition resulting from impaired CNS venous drainage in multiple sclerosis (MS) patients. Venous balloon angioplasty (BA) has been performed as a treatment for CCSVI, although a […]

Authors: M Arata1, P DeGuzman2, F DeBarge-Igoe3 Institutions: 1Synergy Health Concepts, Newport Beach, CA, 2Synergy Health, Newport Beach, CA Enter Objectives / Purpose Statement: Patients seeking treatment for CCSVI at our clinic commonly present with symptoms of autonomic dysfunction: fatigue, interrupted sleep, cognitive impairment, bowel and/or bladder dysfunction, thermal intolerance. Recent analysis by Zohara Sternberg […]

Authors: M Arata1, F DeBarge-Igoe2, P Grewal3, S Cen4 Institutions: 1Synergy Health Concepts, Newport Beach, CA, 2Synergy Health, Newport Beach, CA, 3Pacific Interventionalists, Newport Beach, CA, 4Division of Biokinesiology and Physical Therapy University of Southern California, Los Angeles, CA Enter Objectives / Purpose Statement: Autonomic dysfunction has been identified as a co-morbid syndrome in patients […]

Chronic CerebroSpinal Venous Insufficiency (CCSVI) has been described as a hemodynamic disturbance of the CNS venous drainage. The theory being that CCSVI results from obstructing lesions of the extra-cranial veins in the CNS drainage pathway. Venous hypertension, as a result of the impaired venous drainage seen with CCSVI, is postulated to play a role in […]

Michael Arata, MD, Frances DeBarge-Igoe, RN, Piay DeGuzman Synergy Health Concepts, Newport Beach, CA. BACKGROUND: Jugular venous angioplasty has been performed as a treatment for a condition described as CCSVI. The efficacy of this treatment been challenged as being attributed to a placebo effect or that objective data is lacking and reported responses to treatment […]

Michael Arata, MD1;Prabhjot (Nina) Grewal, MD1; Steven Cen, PhD2; Frances DeBarge-Igoe, RN1. 1Synergy Health Concepts, Newport Beach, CA 2USC Dept of Biokinesiology and Physical Therapy PURPOSE: to evaluate the changes in blood pressure that occur following jugular vein balloon dilation in patients exhibiting symptomatic autonomic dysfunction. MATERIALS AND METHODS: a retrospective chart review was performed […]

M. ARATA1, S. Cen2; BACKGROUND: The FDA recently stated, “the criteria used to diagnose CCSVI have not been adequately established. Therefore, data to support CCSVI as a clinical entity on its own or its relationship with MS are inconclusive and at times, contradictory.” Patients seeking treatment for CCSVI present with a number of symptoms that […]

EM Haacke1,2, PhD, D Utriainen1, BS, S Sethi1, MS, W Feng2, PhD, JJ Hewett3, MD, M Arata3, MD 1MR Innovations, 2Wayne State University, 3Pacific Interventionalists INTRODUCTION: Quantitative imaging of CCSVI using magnetic resonance imaging (MRI) provides an opportunity to study not just anatomical abnormalities1-8 but also the ability to quantify flow2,3,4,7,9. These two pieces of […]